PL-002 Synthesis and antimicrobial activity of the novel siderophore sulfactam BAL30072

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چکیده

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Activity of the siderophore monobactam BAL30072 against multiresistant non-fermenters.

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OBJECTIVES New antibiotics that are active against multidrug-resistant (MDR) Acinetobacter baumannii are urgently needed. BAL30072, a siderophore monosulfactam antibiotic that rapidly penetrates the outer membrane of A. baumannii and has potent activity against most isolates, including those harbouring AmpC β-lactamases and metallo- (class B) or OXA- (class D) carbapenemases, is being developed...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2011

ISSN: 1201-9712

DOI: 10.1016/s1201-9712(11)60065-9